The Cul3 ubiquitin ligase engages Insomniac as an adaptor to impact sleep and synaptic homeostasis.
(2025). Li Q, Lim KY, Altawell R, Verderose F, Li X, Dong W, Martinez J, Dickman D, Stavropoulos N.
PLoS Genetics 21(1):e1011574. PDF
A heteromeric nicotinic acetylcholine receptor promotes sleep by relaying GABAergic signals within a locus of motor and sensory integration.
(2024). Yumita T, Ahamed H, Hatch HAM, Cossentino I, Louka C, Stavropoulos N.
Neuronal knockdown of Cullin3 as a Drosophila model of autism spectrum disorder.
(2024). Tener SJ, Lin Z, Park SJ, Oraedu K, Ulgherait M, Van Beek E, Martínez-Muñiz A, Pantalia M, Gatto JA, Volpi J, Stavropoulos N, Ja WW, Canman JC, Shirasu-Hiza M.
insomniac links the development and function of a sleep regulatory circuit.
(2021). Li Q, Jang H, Lim KY, Lessing A, Stavropoulos N.
Cul3 and insomniac are required for rapid ubiquitination of postsynaptic targets and retrograde homeostatic signaling.
(2019). Kikuma K, Li X, Perry S, Li Q, Goel P, Chen C, Kim D, Stavropoulos N, Dickman D.
Nature Communications 10(1):2998 PDF
Elementary sensory-motor transformations underlying olfactory navigation in walking fruit-flies.
(2018). Álvarez-Salvado E, Licata AM, Connor EG, McHugh MK, King BM, Stavropoulos N, Victor JD, Crimaldi JP, Nagel KI.
A bidirectional relationship between sleep and oxidative stress in Drosophila.
(2018). Hill VM, O'Connor RM, Sissoko GB, Irobunda IS, Leong S, Canman JC, Stavropoulos N, Shirasu-Hiza M.
PLoS Biology 16(7): e2005206. PDF
Conserved properties of Drosophila Insomniac link sleep regulation and synaptic function.
(2017). Li Q, Kellner DA, Hatch HAM, Yumita T, Sanchez S, Machold RP, Frank CA, Stavropoulos N.
PLoS Genetics 13(5):e1006815. PDF
Evaluation of ligand-inducible expression systems for conditional neuronal manipulations of sleep in Drosophila.
(2016). Li Q, Stavropoulos N.
G3: Genes | Genomes | Genetics 6(10):3351-3359. PDF
insomniac and Cullin-3 regulate sleep and wakefulness in Drosophila.
(2011). Stavropoulos N, Young MW.
Identification of developmentally specific enhancers for Tsix in the regulation of X chromosome inactivation.
(2005). Stavropoulos N, Rowntree RK, Lee JT.
Mol Cell Biol. 25:2757-69. PDF
A functional role for Tsix transcription in blocking Xist RNA accumulation but not in X-chromosome choice.
(2001). Stavropoulos N, Lu N, Lee JT.
Proc Natl Acad Sci USA 98:10232-7. PDF Commentary
Further examination of the Xist promoter-switch hypothesis in X inactivation: evidence against the existence and function of a P(0) promoter. (1999). Warshawsky D*, Stavropoulos N*, Lee JT.
Proc Natl Acad Sci USA 96:14424-9. PDF